Allergens

No priority allergen declared in the ingredient list.

NB To give it to your pharmacist or doctor.
VITOLI SLEEP – PRECAUTIONS
Side effects
The different ingredients of the Vitoli SOMMEIL product present little particular toxicity or
serious. However, some users have reported some side effects such as drowsiness, discomfort
headache, dizziness, depressive symptoms, decreased alertness, excitement, irritability, discomfort, or
mild gastrointestinal disturbances. The clinical information we currently have
show, however, that the Vitoli SOMMEIL product has undeniable effectiveness with a profile
reassuring side effects.
It is always possible that hypersensitivity (e.g. allergy) to one of the ingredients of the preparation may occur.
manifest. In such a case it is recommended to discontinue use and consult a healthcare professional.
health if serious allergy symptoms persist.
Contraindications
Given the possibility of drowsiness, driving or any other activity requiring
large concentration should be avoided, particularly within 4 to 6 hours of taking it. Melatonin
could be contraindicated in the presence of depression, diabetes, hepatic disorders and epilepsy, and with
NIFEDIPINE (= ADALAT trade name) (decreased effect of NIFEDIPINE). However, we believe
that cases of depression and diabetes should constitute cases of monitoring (and not strict contraindications) for which improving sleep could be greatly beneficial.

Interactions
Theoretically, the Vitoli SOMMEIL product could increase the sedative effect of alcohol, barbiturates,
benzodiazepines, any other tranquilizer, hypnotic or sedative, or even certain others
natural products such as kava, chamomile, lemon balm, etc.
Due to the presence of melatonin, the Vitoli SOMMEIL product could reduce the effectiveness of certain
medications for hypertension. However, it is also known that improved sleep and
Reducing stress and anxiety helps reduce blood pressure (monitoring case). It is also
recommended to avoid it during immunosuppressive treatment (melatonin could affect the function
immune).
Fluvoxamine and Melatonin: by inhibiting CYP1A2, fluvoxamine could increase, so
important, the plasma concentrations of Melatonin, therefore an increase in the effects
possible undesirables. Avoid, due to potential excessive drowsiness in the patient.
Olive quality extracts could lower blood pressure, improve glucose management and
reduce blood clotting. However, the dose used is the food dose consumed on average
in the Mediterranean diet and it is not linked to any significant interaction effects. Health Canada
did not report this risk as significant.

Pregnancy and breast feeding
No safety data is available for certain ingredients or certain contraindications
being reported for others, it is contraindicated for use in the presence of pregnancy and not
Recommended to use if you or are breastfeeding.
Caution
The content of medicinal plants naturally varies depending on the production site or conditions
extraction. There is therefore a lot of variation in the composition of the ingredients available in a
brand of products to another. It is strongly recommended to use quality products, these
being standardized to contain sufficient quantities of active substances for each plant, which
ensures their effectiveness, confirms the origin of the plant and safety. Canadian regulations do not require
not companies to respect these standards; the majority of plant extracts on the market are not
standardized. The information contained in this document applies only to products of the
range
Vitoli.
According to Health Canada (2016), the use of melatonin in children and adolescents
should be used with caution, although it is indeed used on occasion depending on
current data. This should only be done on the recommendation of a
healthcare professional.
André Perreault, pharmacist,
Professional services
Idunn Technologies
Revised by Jean-Yves Dionne,
Apothecary Academy (www.apothecary.ca)
References :
1.Natural Medicines Comprehensive Database, Therapeutic Research Faculty, 2010
2.Passporthealth.net.Valerian. www.passeportsante.net
3.The Review of Natural Products, 6th edition, 2010
4.Barnes J. Et Al. Herbal Medicines, 2nd edition, Pharmaceutical Press, 2002
5.Health Canada, Natural Health Products Database
6.Facts and Comparisons, The Lawrence review of natural products, 1998
7.Herbal Companion to AHFS DI, American Society of Health-System Pharmacist, 2001
||
NB To give to your pharmacist or doctor.
VITOLI SLEEP - PRECAUTIONS
Side effects
The different ingredients of Vitoli SOMMEIL do not present any particular or serious toxicity.
serious toxicity. However, some users have reported side effects such as drowsiness, headaches, dizziness
headaches, dizziness, depressive symptoms, decreased alertness, excitement, irritability, discomfort, or mild gastrointestinal
mild gastrointestinal disorders. However, the clinical information currently available to us shows that Vitoli SOM
that Vitoli SOMMEIL is undeniably effective and has a reassuring side effect profile.
with a reassuring side effect profile.
It is always possible that a hypersensitivity (eg allergy) to one of the ingredients of the preparation may occur.
to one of the ingredients of the preparation. In such a case, it is recommended to stop using the product and to consult a health professional if
if serious symptoms of allergy persist.
Contraindications
Due to possible drowsiness, driving or any other activity requiring high concentration should be avoided, especially in
concentration should be avoided, especially during the first 4 to 6 hours after use. Melatonin
may be contraindicated in the presence of depression, diabetes, liver disorders and epilepsy, and with
NIFEDIPINE (= ADALAT trade name) (decreased effect of NIFEDIPINE). However, we believe that
However, we believe that depression and diabetes should be monitored (not strictly contraindicated) and that improved sleep could be of great benefit.

Interactions
Theoretically, Vitoli SOMMEIL could increase the sedative effect of alcohol, barbiturates
benzodiazepines, any other tranquilizer, hypnotic or sedative, or even some other natural products such as
natural products such as kava, chamomile, lemon balm, etc.
Because of the presence of melatonin, Vitoli SOMMEIL could reduce the effectiveness of certain
the effectiveness of certain anti-hypertensive drugs. However, it is also known that the improvement of sleep and the
stress and anxiety helps to reduce blood pressure (monitoring cases). It is also
recommended to avoid it during immunosuppressive treatment (melatonin could affect the immune function).
immune function).
Fluvoxamine and Melatonin: By inhibiting CYP1A2, fluvoxamine may significantly increase plasma concentrations of melatonin.
plasma concentrations of Melatonin, thus an increase in possible adverse effects.
possible adverse effects. To be avoided, due to a potential excessive drowsiness in the patient.
Olive quality extracts may lower blood pressure, improve glucose management and
reduce blood clotting. However, the dose used is the average dietary dose consumed
in the Mediterranean diet and is not related to any significant interaction effects. Health Canada
has not reported this risk as significant.

Pregnancy and lactation
No safety data being available for some ingredients or some contraindications being reported for others, the
contraindications for others, it is contraindicated to use it in pregnancy and not recommended to use it if you or your child is pregnant.
recommended if you are pregnant or breastfeeding.
Cautionary note
The content of medicinal plants varies naturally according to the site of production or according to the conditions of
extraction conditions. There are therefore many variations in the composition of the ingredients available from one brand of
from one brand of product to another. It is strongly recommended to use quality products, which are standardized to contain
to contain sufficient quantities of active substances for each plant, which ensures their effectiveness, confirms the
This ensures their effectiveness, confirms the origin of the plant and safety. Canadian regulations do not require companies to
companies to respect these standards; the majority of plant extracts on the market are not standardized.
standardized. The information contained in this document applies only to the products of the
line
Vitoli line.
According to Health Canada (2016), the use of melatonin in children and adolescents
should be treated with caution, although it is indeed used occasionally based on
current evidence. This should only be done on the recommendation of a
health professional.
André Perreault, pharmacist,
Professional Services
Idunn Technologies
Reviewed by Jean-Yves Dionne,
Academy of Apothecaries (www.apothecaries.ca)
References :
1.Natural Medicines Comprehensive Database, Therapeutic Research Faculty, 2010
2.Passporthealth.net.Valerian. www.passeportsante.net
3 The Review of Natural Products, 6th edition, 2010
4.Barnes J. et al. Herbal Medicines, 2nd edition, Pharmaceutical Press, 2002
5 Health Canada, Natural Health Products Database
Facts and Comparisons, The Lawrence review of natural products, 1998
7 Herbal Companion to AHFS DI, American Society of Health-System Pharmacist, 2001

Ingredients

Taken from the manufacturer's label. For severe allergies, always check the package.