Allergens

No priority allergen declared in the ingredient list.

NB To give it to your pharmacist or doctor.
VITOLI MEMORY AND COGNITIVE HEALTH - PRECAUTIONS
Side effects
The different ingredients of the Vitoli MEMORY AND COGNITIVE HEALTH product present little toxicity
particular or serious. Some users of Ginko biloba have reported some side effects
such a slight risk of gastrointestinal effects, headache, or dizziness. Scientific literature
reports that during long-term use, some patients experienced bleeding (Ginkgo
biloba*5; controversial observation). Rare users of this ingredient have also experienced reactions
skin allergies. These reactions and headaches could be due to poor extract quality;
presence of ginkolic acid coming from the fruit or branch and normally absent from good extracts
of leaves. The clinical information we currently have shows us that Vitoli MEMORY
AND COGNITIVE HEALTH has a reassuring side effect profile.
Contraindications
The Vitoli MEMORY AND COGNITIVE HEALTH product should be avoided (stop for at least 7 days or according to
the opinion of the doctor) in patients undergoing surgery, operation, transplant or other high-risk intervention
bleeding. It would also be contraindicated in patients taking antiplatelets or anticoagulants (*4). Of
more in a patient taking Nifedipine (Adalat or other generic), increased monitoring would be
recommended since there is a possibility of increasing the effect of Nifedipine by Ginkgo Biloba (*3).
Avoid the product in patients who have previously had an allergy to sumac, poison ivy, and poisonous peel.
mango. Although the cases listed are anecdotal (*2 and *7), it could be avoided as a precaution in
epileptic patients on anticonvulsants, both because of Ginkgo and folic acid.
Interactions
Possible increase in the effect of nifedipine (*3). Possible increase in the effect of antiplatelet drugs.
Possible increase in the effect of anticoagulants (*4). Possible reduction in the effect of certain
anticonvulsants (phenytoin, phenobarbital, primidone). The product should not be used in the rare
patients who are taking one of the following two (2) medications: BUROSOMAB and ERDAFITINIB.
Olive quality extracts could lower blood pressure, improve glucose management and
reduce blood clotting. However, the dose used is the food dose consumed on average
in the Mediterranean diet and it is not linked to any significant interaction effects. Health Canada
did not report this risk as significant.
Pregnancy and breast feeding
It appears prudent to avoid taking Vitoli MEMORY AND COGNITIVE HEALTH during pregnancy or
breastfeeding.
www.vitoli.ca - professionals@vitoli.ca
(438) 794-3372
Caution
The content of medicinal plants varies naturally or depending on the extraction conditions. So there is
many variations in the composition of ingredients available from one product brand to another
other. It is strongly recommended to use quality products, these being standardized to contain
sufficient quantities of active substances for each plant, which ensures their effectiveness, confirms
the origin of the plant and safety. Canadian regulations do not require companies to respect these
standards; the majority of plant extracts on the market are not standardized. Idunn Technologies
use only standardized ingredients for Vitoli products and the information contained in
This document applies only to these products.
If you are taking prescription medications and are unsure, check with your pharmacist to see if they are
compatible with the Vitoli MEMORY AND COGNITIVE HEALTH product before consuming it.
It is always possible that hypersensitivity (e.g. allergy) to one of the ingredients of the preparation may occur.
manifest. In such a case it is recommended to discontinue use and consult a healthcare professional.
health if serious allergy symptoms persist.
André Perreault, pharmacist,
Professional services
Idunn Technologies
Revised by Jean-Yves Dionne,
Apothecary Academy (www.apothecary.ca)
References :
1-Pregnancy and breastfeeding – Therapeutic guide, (2nd edition, 2013)
* 2 - Granger AS. Ginkgo biloba precipitating epileptic seizures. Age Aging 2001;30:523-5
* 3- Yoshioka, et al. Studies on interactions between functional foods or dietary supplements and
medicines. IV. Effects of ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in
healthy volunteers. Biol.Pharm.Bull. 2004;27(12):2006-2009.
*4- Gaudineau C, Beckerman R, Welbourn S, Auclair K. Inhibition of human P450 enzymes by multiple
constituents of the Ginkgo biloba extract. Biochem Biophys Res Comm 2004;318:1072–8
*5- Bent S, Goldberg H, Padula A, Avins AL. Spontaneous bleeding associated with Ginkgo biloba: a case report and
systematic review of the literature. J Gen Intern Med 2005;20;657-61.
*6- Dugoua JJ, Mills E, Perri D, Koren G. Safety and efficacy of ginkgo (Ginkgo biloba) during pregnancy and lactation.
Can J Clin Pharmacol 2006;13:e277-84.
*7- Gregory PJ. Seizure associated with Ginkgo biloba? Ann Intern Med 2001;134:344.
8.-Natural Medicines Comprehensive Database, Therapeutic Research Faculty, 2018
9.-The Review of Natural Products, 6th edition, 2010
10.-Health Canada, Natural Health Products Database
11.-Facts and Comparisons, The Lawrence review of natural products, 1998 12.-Rx
||
NB To give to your pharmacist or physician.
VITOLI MEMORY AND COGNITIVE HEALTH - PRECAUTIONS
Side effects
The different ingredients of Vitoli MEMORY AND COGNITIVE HEALTH have little or no specific or serious toxicity.
or serious toxicity. Some users of Ginko biloba have reported some side effects such as a slight risk of gastric effect
such as a slight risk of gastrointestinal effects, headaches, or dizziness. The scientific literature
reports that during long-term use, some patients have experienced bleeding (Ginkgo
biloba*5; controversial observation). Some rare users of this ingredient have also experienced skin
allergic skin reactions. These reactions and the headaches could be due to the poor quality of the extract;
presence of gingkolic acid coming from the fruit or the branch and normally absent from good extracts
of leaves. The clinical information we have at present shows that Vitoli MEMORY
AND COGNITIVE HEALTH has a reassuring side effect profile.
Contraindications
Vitoli MEMORY AND COGNITIVE HEALTH should be avoided (stopped for at least 7 days or as advised by the doctor) in
physician's advice) in patients undergoing surgery, operation, transplantation or any other procedure with risk of bleeding.
bleeding. It would also be contraindicated in patients on antiplatelet or anticoagulant drugs (*4). From
In addition, in a patient taking Nifedipine (Adalat or other generic), increased monitoring would be
recommended since there is a possibility of an increase in the effect of Nifedipine by Ginkgo Biloba (*3).
Avoid the product in patients with a previous allergy to sumac, poison ivy, and mango peel.
mango peel. Although reported cases are anecdotal (*2 and *7), it should be avoided as a precaution in
epileptic patients on anticonvulsants, both because of the Ginkgo and the folic acid.
Interactions
Possible increase in the effect of nifedipine (*3). Possible increase in the effect of antiplatelet drugs.
Possible increase in the effect of anticoagulants (*4). Possible decrease in the effect of some
anticonvulsants (phenytoin, phenobarbital, primidone). The product should not be used in the rare
patients who are on one of the following two (2) drugs: BUROSOMAB and ERDAFITINIB.
Olive quality extracts may lower blood pressure, improve glucose management and reduce blood clotting.
reduce blood clotting. However, the dose used is the average dietary dose consumed
in the Mediterranean diet and is not related to any significant interaction effects. Health Canada
has not reported this risk as significant.
Pregnancy and breastfeeding
It appears prudent to avoid taking Vitoli MEMORY AND COGNITIVE HEALTH during pregnancy or lactation.
breast feeding.
www.vitoli.ca - professionals@vitoli.ca
(438) 794-3372
Cautionary note
The content of medicinal plants varies naturally or according to the extraction conditions. Therefore, there are
There is therefore a lot of variation in the composition of the ingredients available from one brand of product to another.
another. It is strongly recommended to use quality products, which are standardized to contain
sufficient quantities of active substances for each plant, which ensures their effectiveness, confirms
the origin of the plant and safety. Canadian regulations do not require companies to meet these standards.
standards; the majority of plant extracts on the market are not standardized. Idunn Technologies
uses only standardized ingredients for its Vitoli products and the information contained in this document applies only to those
this document applies only to these products.
If you are taking prescription drugs and are unsure, check with your pharmacist to see if they are
compatible with Vitoli MEMORY AND COGNITIVE HEALTH before taking it.
It is always possible that a hypersensitivity (ex: allergy) to one of the ingredients of the preparation may occur.
to one of the ingredients of the preparation. In such a case, it is recommended to stop using the product and to consult a health professional if serious symptoms of allergy occur.
if serious allergy symptoms persist.
André Perreault, pharmacist,
Professional Services
Idunn Technologies
Reviewed by Jean-Yves Dionne,
Academy of Apothecaries (www.apothecaries.ca)
References:
1-Fat and Breastfeeding - A Therapeutic Guide, (2nd Edition, 2013)
* 2 - Granger AS. Ginkgo biloba precipitating epileptic seizures. Aging 2001;30:523-5
* 3- Yoshioka, et al. Studies on interactions between functional foods or dietary supplements and
medicines. IV. Effects of ginkgo biloba leaf extract on the pharmacokinetics and pharmacodynamics of nifedipine in
healthy volunteers. Biol.Pharm.Bull. 2004;27(12):2006-2009.
*4- Gaudineau C, Beckerman R, Welbourn S, Auclair K. Inhibition of human P450 enzymes by multiple
constituents of the Ginkgo biloba extract. Biochem
Biophys Res Comm 2004;318:1072-8
*5- Bent S, Goldberg H, Padula A, Avins AL. Spontaneous bleeding associated with Ginkgo biloba: case report and systematic review of the literature.
systematic review of the literature. J Gen Intern Med 2005;20;657-61.
*6- Dugoua JJ, Mills E, Perri D, Koren G. Safety and efficacy of ginkgo (Ginkgo biloba) during pregnancy and lactation.
Can J Clin Pharmacol 2006;13:e277-84.
*7- Gregory PJ. Epileptic seizure associated with Ginkgo biloba? Ann Intern Med 2001;134:344.
8.-Natural Medicines Comprehensive Database, Faculty of Therapeutic Research, 2018.
9.-The Review of Natural Products, 6th edition, 2010
10.-Health Canada, Natural Health Products Database.
11.-Facts and comparisons, The Lawrence review of natural products, 1998 12.-Rx

Ingredients

Taken from the manufacturer's label. For severe allergies, always check the package.